Therapeutic Efficacy of Alpha-Lipoic Acid against Acute Myocardial Infarction and Chronic Left Ventricular Remodeling in Mice

Figure 3

Short-axis cross sections of hearts from control and ALA-treated mice assessed by cardiac MRI and at necropsy. The top panel illustrates typical mid-ventricular, short-axis cardiac MR images from control mice 1 d post-AMI, control mice 8 wk post-AMI and ALA-treated mice 8 wk post-AMI. The bottom panel shows photographs of the corresponding short-axis tissue sections. The pronounced infarct expansion observed in control mice (center panel) was far less evident in mice treated with ALA (panel at right).