Therapeutic Efficacy of Alpha-Lipoic Acid against Acute Myocardial Infarction and Chronic Left Ventricular Remodeling in Mice

Table 1

Heart rates and anatomic features during 8-week follow-up in LVR study.

Group	Heart rate (bpm)				Cardiac morphometric data at day 56
	Baseline	Day 1	Day 28	Day 56	LV vol (μm^3)	Ht/B Wt^†	IF extent^‡
H2O	326 ± 21	462 ± 66	380 ± 38	347 ± 17	130.6 ± 33.4	0.67 ± 0.05	40.9 ± 3.7
ALA	360 ± 28	489 ± 47	318 ± 38	358 ± 17	85.6 ± 10.7	0.61 ± 0.03	32.9 ± 2.2
value	NS	NS	NS	NS	<0.05	NS	<0.001

Left ventricular volume; ^†heart-to-body weight ratio (%); ^‡infarct extent (%).