Adaptive Autophagy Offers Cardiorenal Protection in Rats with Acute Myocardial Infarction

Figure 3

Autophagy inhibition aggravates apoptosis and injury and autophagy changes in AC16 and HK-2 cells. (a) Activity of caspase-3 in AC16 cells. (b) Activity of caspase-3 and Levels of KIM1 and NGAL in HK-2 cells. (c) Western blot analysis of LC3-II, p62, and Beclin1 levels in AC16 cells. (d) Western blot analysis of LC3-II, p62, and Beclin1 levels in the HK-2 cells. CON = normal group. 3-MA = normal + 3-methyladenine. MOD = hypoxic cell group. MOD + 3-MA = hypoxic cell group + 3-methyladenine. (n = 3).

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