Adaptive Autophagy Offers Cardiorenal Protection in Rats with Acute Myocardial Infarction

Table 1

Hemodynamic changes in the heart of rats after AMI.

	Week 2		Week 4
	Sham	Model	Sham	Model
LVSP	149.2 ± 8.2	108.7 ± 9.6	170.4 ± 5.2	129.6 ± 4.5
LVEDP	−3.4 ± 4.3	5.5 ± 3.3	−9.5 ± 1.0	31.3 ± 5.5
+dP/dt max	5495.0 ± 349.4	2865.2 ± 259.5	6209.5 ± 233.2	2418.0 ± 213.0
-dP/dt max	−4618.5 ± 331.8	−2526.3 ± 249.5	−5292.6 ± 247.8	−2405.4 ± 126.4

; , model compared with sham. , model of 2 weeks compared with 4 weeks. LVSP, left ventricular systolic pressure; LVEDP, left ventricular end-diastolic pressure; ±dp/dtmax, maximum rate of pressure rise/drop in the left ventricle. Data are expressed as the mean ± SEM (n = 6).