Research Article

Risk Factors for No-Reflow in Patients with ST-Elevation Myocardial Infarction Who Underwent Percutaneous Coronary Intervention: A Case-Control Study

Table 2

Univariable analysis for no-reflow.

VariablesUnivariable analysis
OR (95% CI)

Clinical data
 Age1.015 (1.000–1.030)0.052
 Male1.171 (0.779–1.762)0.448
 Hypertension1.141 (0.825–1.577)0.426
 Diabetes mellitus1.197 (0.819–1.749)0.353
 Smoking0.983 (0.694–1.393)0.923
 Prior PCI0.638 (0.312–1.307)0.220
 Preinfarction angina1.158 (0.836–1.605)0.377

Medication before MI
 Aspirin0.872 (0.502–1.513)0.625
 ACEI1.241 (0.752–2.050)0.398
β-Blocker1.558 (0.781–3.108)0.208
 Calcium channel blockers1.106 (0.754–1.624)0.606
 Statin1.238 (0.466–3.290)0.669
 Time-to-hospital admission0.985 (0.976–0.995)0.002

Physical findings on admission
 Systolic blood pressure0.995 (0.987–1.003)0.209
 Diastolic blood pressure1.000 (0.987–1.013)0.992
 Heart rate1.026 (1.016–1.037)<0.001

Laboratory indicators
 Plasma glucose1.088 (1.042–1.135)<0.001
 hsCRP1.024 (1.009–1.039)0.001
 PAB0.026 (0.002–0.385)0.008
 hsCRP/PAB1.005 (1.003–1.008)<0.001
 Albumin0.995 (0.973–1.019)0.701
 hsCRP/albumin1.551 (0.963–2.499)0.071
 Neutrophil count1.172 (1.117–1.229)<0.001
 LDL-C0.989 (0.930–1.052)0.733
 Triglycerides1.013 (0.958–1.070)0.659
 Killip classes >10.648 (0.433–0.970)0.035

Treatment before or during the procedure
 Glycoprotein IIb/IIIa inhibitor1.608 (0.936–2.764)0.086
 Intraaortic balloon pump0.203 (0.128–0.320)<0.001

Angiography
 Multivessel disease1.174 (0.710–1.702)0.396
 Infarct-related artery0.557 (0.325–0.954)0.033

Procedure
 Aspiration thrombectomy0.247 (0.169–0.361)<0.001
 After dilation1.302 (0.940–1.801)0.112
 Stent diameter1.114 (0.894–1.388)0.334
 Total stent length1.002 (0.991–1.012)0.752

PCI, percutaneous coronary intervention; MI, myocardial infarction; ACEI, angiotensin-converting enzyme inhibitor; hsCRP, high-sensitivity C-reactive protein; PAB, prealbumin; LDL-C, low-density lipoprotein cholesterol.