Expression of TLR4 Is Upregulated in Patients with Sporadic Acute Stanford Type A Aortic Dissection

Table 3

Multiple logistic regression analysis of factors associated with TAAD.

	Model 1			Model 2
	OR	95% CI	value	OR	95% CI	value
Male sex (%)	2.58	0.73–9.05	0.14	3.23	0.53–19.8	0.21
Age (years)	0.98	0.91–1.05	0.55	0.95	0.85–1.06	0.35
Smoking (n[%])	1.04	0.84–1.21	0.64	1.08	0.90–1.27	0.51
Hypertension (n[%])	2.65	0.80–8.74	0.11	2.34	0.43–12.8	0.33
D-dimer (mg/L)	1.66	1.20–2.29	0.002	1.34	1.04–1.73	0.02
WBC (×10^9/L)	1.15	0.97–1.37	0.12	1.06	0.82–1.38	0.65
TC (mmol/L)	1.21	0.58–2.47	0.62	1.47	0.55–3.93	0.44
LDL-C (mol/L)	0.78	0.23–2.61	0.68	0.95	0.65–1.41	0.81
HDL-C (mol/L)	0.64	0.05–7.70	0.73	0.48	0.01–18.3	0.69
CCL5 (ng/ml)				0.031	0.005–0.179	<0.001
IL-1β (pg/ml)	2.04	1.13–3.71	0.019
	R^2 = 0.65,			R^2 = 0.83,

TAAD: acute Stanford type A aortic dissection; OR: odds ratio; 95% CI: 95% confidence intervals; WBC: white blood cell; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; IL-1β: interleukin-1β; CCL5: CC chemokine ligand 5.