Exogenous Hydrogen Sulfide Activates PI3K/Akt/eNOS Pathway to Improve Replicative Senescence in Human Umbilical Vein Endothelial Cells

<div>Impact of NaHS and LY294002 on HUVECs growth. No statistical significances were observed among groups. CON: control groups, HUVECs without any treatment. NaHS: HUVECs exposed to 200 <i>μ</i>mol/L NaHS. LY: HUVECs exposed to 10 <i>μ</i>mol/L LY294002. NaHS + LY: HUVECs exposed to 200 <i>μ</i>mol/L NaHS and 10 <i>μ</i>mol/L LY294002 simultaneously.</div>

Cardiology Research and Practice

fig5

Figure 5

Figure 5: Exogenous Hydrogen Sulfide Activates PI3K/Akt/eNOS Pathway to Improve Replicative Senescence in Human Umbilical Vein Endothelial Cells 