SFRP4 Reduces Atherosclerosis Plaque Formation in ApoE Deficient Mice

Figure 4

Typical characteristics of DEGs in the aorta of ApoE KO mice. (a) Principal components analysis (PCA) shows the difference of the samples. (b) Volcano plots show the DEGs expression based on the RNA sequences analysis. (c) Analysis of the DEGs was conducted utilizing the DESeq software by contrasting the Ad-GFP and Ad-SFRP4 cohort. The expression levels are denoted by colors, with red (high expression) and blue (low expression), and are proportional to their brightness (see color bar). n = 3 for each cohort.

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