Altered Reward Circuit Function Moderates the Relationship between Childhood Maltreatment and Depression Severity in Adolescents

<div>Between-group differences in RSFC of left posterior globus pallidus and right DMPFC between AO-MDD and HCs. Abbreviations: AO-MDD: adolescent-onset major depressive disorder; HCs: heathy controls; RSFC: resting-state functional connectivity; pGP: posterior globus pallidus; DMPFC: dorsolateral prefrontal.</div>

Depression and Anxiety

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Figure 1

Figure 1: Altered Reward Circuit Function Moderates the Relationship between Childhood Maltreatment and Depression Severity in Adolescents 