Altered Reward Circuit Function Moderates the Relationship between Childhood Maltreatment and Depression Severity in Adolescents

Table 1

Demographic and clinical features of participants.

Variables	AO-MDD ()	HCs ()
Gender (male/female)	61/14	31/49	29.096	<0.001
Age (years)			-0.429	0.669
Education (years)			-0.410	0.682
Duration of illness (month)		—	—	—
HAMD-17			40.242	<0.001
HAMA			33.02	<0.001
CTQ total			14.240	<0.001
Abuse			10.253	<0.001
Neglect			8.633	<0.001
Mean framewise displacement			0.616	0.539

Abbreviations: AO-MDD: adolescent-onset major depressive disorder; HCs: heathy controls; HAMD-17: 17-item Hamilton Depression Rating Scale; CTQ: Childhood Trauma Questionnaire, Hamilton Anxiety Scale.