Advances in Zebrafish as a Comprehensive Model of Mental Disorders

Figure 6

Pathology for different mechanisms of depression. The pathology of depression falls into six categories, including disorder of the HPA axis, abnormal of BDNF signaling pathway, disorder of neurotransmitter, depression caused by genetic or genetic mutations, and metabolomics or disorders of the immune system caused by some diseases (such as metabolic diseases, disorder of energy metabolism, gut microbes, amino acids metabolism, and lipid metabolism), which are complicated by depression. Reproduced with permission from [261].