Research Article

Loneliness during the COVID-19 Pandemic in Patients with Burning Mouth Syndrome: A Multicentric Case-Control Italian Study

Table 6

Disease onset; type of treatment and number of consultations prior to the diagnosis; type of referral and number of referrals; intensity, quality, and pattern of pain; prevalence of oral symptoms; and location in 100 BMS patients.

Disease onset (months)
30 [12-49.5]
Number of doctors consulted prior to diagnosis of BMS
2 [1-3]
ReferralsFrequency (%)
 Physician52 (52)
 Maxillofacial surgeon1 (1)
 Otolaryngologist30 (30)
 Gastroenterologist14 (14)
 Dentist82 (82)
 Dermatologist1 (1)
 Neurologist4 (4)
 Psychiatrist1 (1)
 Other8 (8)
Disease onset before pandemicFrequency (%)
63 (63)
Disease onset after pandemicFrequency (%)
37(37)
Worsening of disease during pandemicFrequency (%)
27 (27)
Time of worsening (months)Median; IQR
12 [5-13]
Treatment with psychotropic drugsFrequency (%)
62 (62)
Treatment with PEAFrequency (%)
29 (29)
Increasing dosage after pandemic outbreak (yes)13 (13)
PainMedian; IQR
 NRS6 [4-8]
 SF-MPQ6 [1-13.25]
Pattern of symptomsFrequency (%)
 Same in the morning/afternoon/evening14 (14)
 Worse in the afternoon/evening32 (32)
 Worse in the morning9 (9)
 Changing day by day45 (45)
 Present in the night36 (36)
Oral symptomsFrequency (%)
 Burning100 (100)
 Only burning11 (11)
 Burning+additional symptoms89 (89)
 Intraoral foreign body sensation21 (21)
 Xerostomia63 (63)
 Dysgeusia42 (42)
 Globus pharyngeus13 (13)
 Subjective change in tongue morphology12 (12)
 Subjective change in tongue color32 (32)
 Sialorrhea17 (17)
 Itching10 (10)
 Tingling sensation24 (24)
 Occlusal dysesthesia17 (17)
 Oral dyskinesia10 (10)
 Dysosmia7 (7)
 Subjective halitosis29 (29)
Location of pain/burningFrequency (%)
 Burning/pain diffuse to entire oral mucosa40 (30)
 Burning/pain localized in one or more sites of oral mucosa60 (60)
 Tongue80 (80)
 Lips38 (38)
 Palate20 (20)
 Gums38 (38)
 Cheeks38 (38)
 Floor of the mouth19 (19)
 Trigone3 (3)

Abbreviations: BMS: burning mouth syndrome; PEA: palmitoylethanolamide; NRS: Numeric Rating Scale; SF-MPQ: short-form McGill Pain Questionnaire.