Review Article
The Dark and Gloomy Brain: Grey Matter Volume Alterations in Major Depressive Disorder–Fine-Grained Meta-Analyses
Table 2
Significant results of the four peaks belonging to the cluster of GMV atrophy in pure MDD patients versus healthy controls.
| Cluster | Anatomical label | BA | MNI coordinates | Size (mm3) | ALE value | value | score | | | |
| 1 | Left insula | 13 | -46 | 12 | -8 | 3064 | 0.0340712 | <0.00000001 | 5.543614 | Left superior temporal gyrus | 22 | -54 | 6 | 0 | | 0.0178932 | <0.00020437 | 3.534379 | Left insula | 13 | -40 | 4 | 10 | | 0.0176861 | <0.00022831 | 3.504988 | Left insula | 13 | -48 | 10 | 4 | | 0.0132937 | <0.00223949 | 2.842296 |
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