The Dark and Gloomy Brain: Grey Matter Volume Alterations in Major Depressive Disorder–Fine-Grained Meta-Analyses

Table 4

Significant peaks’ results of the two clusters of GMV atrophy in MDD+A patients versus healthy controls.

Cluster	Anatomical label	BA	MNI coordinates			Size (mm^3)	ALE value	value	score
			1	Right insula	13					38	22	-4	4216	0.0269826	<0.00000166	4.649883
Right superior temporal gyrus	21	56		-6	-12		0.0200830	<0.00008093	3.772142
Right claustrum		26		24	2		0.0178103	<0.00027382	3.456300
Right insula	13	48		-4	-6		0.0170445	<0.00041425	3.343091
Right sublobar extranuclear	13	42		6	-16		0.0165700	<0.00053162	3.273233
Right insula	13	48		16	-4		0.0157237	<0.00082873	3.145600
Right insula	13	48		4	-8		0.0141346	<0.00182844	2.906337
Right temporal lobe	38	50		6	-24		0.0130762	<0.00300305	2.747448
2	Left insula	13	-46	12	-8	2952	0.0340717	<0.00000002	5.466796
	Left superior temporal gyrus	22	-54	4	0		0.0182960	<0.00021031	3.526797
	Left insula	13	-40	4	10		0.0176863	<0.00029208	3.438860
	Left insula	13	-48	10	4		0.0132938	<0.00272476	2.779186