Research Article
Pharmacological and Psychological Treatment Have Common and Specific Effects on Brain Activity in Obsessive-Compulsive Disorder
Table 1
Demographic and clinical data presented as the
.
| | SSRI () | CBT () | Controls () | value |
| Age (years) | | | | 1 | Gender (male/female) | 7/10 | 10/7 | 9/11 | 2 | Highest education () | | | | 2 | (i) Elementary school | 1 | 0 | 0 | | (ii) Lower professional | 0 | 2 | 0 | | (iii) Medium professional | 4 | 5 | 8 | | (iv) Higher professional | 12 | 10 | 12 | | Time between scans (weeks) | | | | 3 | OCD subtype () | | | | 2 | (i) Harm and checking | 6 | 9 | | | (ii) Contamination and washing | 3 | 3 | | | (iii) Symmetry and ordering | 4 | 3 | | | (iv) Forbidden thoughts | 3 | 1 | | | (v) Miscellaneous | 1 | 1 | | | Duration of illness (years) | | | | 4 | Comorbidity () | | | | 2 | (i) None | 5 | 5 | | | (ii) Single | 7 | 8 | | | (iii) Multiple (≥2) | 5 | 4 | | | Previous treatment history () | | | | 2 | (i) None | 8 | 9 | | | (ii) SSRI | 2 | 2 | | | (iii) CBT | 5 | 3 | | | (iv) | 2 | 3 | | | Y-BOCS | | | | | (i) Baseline | | | | 4 | (ii) Follow-up | | | | 4 | Responder (yes/no) | 4/13 | 13/4 | | 2 | HAM-A | | | | | (i) Baseline | | | | 4 | (ii) Follow-up | | | | 4 | HAM-D | | | | | (i) Baseline | | | | 4 | (ii) Follow-up | | | | 4 |
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Significant difference between groups, , tested with 1Kruskal-Wallis test, 2chi-squared test, 3one-way ANOVA, or 4Welch’s -test. Scales: Y-BOCS: Yale-Brown Obsessive-Compulsive Scale; HAM-A: Hamilton Anxiety Rating Scale; HAM-D: Hamilton Depression Rating Scale. |