Depression and Anxiety

Research Article

Influence of Depression on Pain and Disability in Patients with Chronic Low Back Pain after Physical Therapy: A Secondary Analysis of a Randomized Controlled Trial

Table 3

Influence of depression on the minimal clinically important difference of pain and disability.


Variables	Adjusted logistic regression model after the 12-week intervention			Adjusted logistic regression model after the 52-week follow-up
Variables	Adjusted OR	95% CI	value	Adjusted OR	95% CI	value

RMDQ MCID
Total	1.041	0.994 to 1.090	0.092	0.987	0.947 to 1.029	0.549
(i) Aquatic exercise	NA	NA	NA	3.328	1.525 to 7.261	0.003^a
(ii) Male	0.360	0.155 to 0.836	0.017^a	NA	NA	NA
(ii) Age	1.066	1.017 to 1.116	0.007^a	NA	NA	NA
CLBP with depression group	1.196	0.859 to 1.664	0.289	0.994	0.857 to 1.153	0.936
(i) Aquatic exercise	NA	NA	NA	2.504	0.577 to 10.872	0.220
(ii) Male	0.079	0.007 to 0.851	0.036^a	NA	NA	NA
(iii) Age	1.044	0.963 to 1.132	0.299	NA	NA	NA
CLBP without depression group	1.062	0.971 to 1.161	0.186	0.991	0.909 to 1.081	0.838
(i) Aquatic exercise	NA	NA	NA	3.709	1.474 to 9.334	0.005^a
(ii) Male	0.564	0.215 to 1.480	0.244	NA	NA	NA
(iii) Age	1.074	1.013 to 1.140	0.017^a	NA	NA	NA
NRS severe MCID
Total	1.021	0.974 to 1.070	0.387	1.019	0.977 to 1.062	0.389
CLBP with depression group	0.905	0.765 to 1.070	0.242	1.161	0.936 to 1.441	0.174
CLBP without depression group	1.048	0.954 to 1.151	0.328	1.057	0.971 to 1.151	0.201
NRS average MCID
Total	1.014	0.972 to 1.057	0.514	0.989	0.948 to 1.032	0.614
CLBP with depression group	0.922	0.757 to 1.122	0.417	0.870	0.702 to 1.078	0.202
CLBP without depression group	1.042	0.956 to 1.134	0.350	1.115	1.018 to 1.221	0.019^a
NRS current MCID
Total	1.016	0.977 to 1.057	0.432	1.020	0.977 to 1.064	0.371
CLBP with depression group	1.021	0.882 to 1.181	0.781	1.095	0.938 to 1.278	0.251
CLBP without depression group	1.029	0.948 to 1.116	0.497	1.047	0.957 to 1.146	0.316

Abbreviations: RMDQ: Roland-Morris disability questionnaire; MCID: minimal clinically important difference; CLBP: chronic low back pain; NRS: numeric rating scale; CI: confidence interval; NA: not applicable, and insufficient data to run the analysis. ^aData statistically significant.