Global Dynamics and Applications of an Epidemiological Model for Hepatitis C Virus Transmission in China

Table 1

Parameters and initial data chosen for the simulation.

Variable and parameter	Description	Initial or default values	Source
Variables
	Susceptible population		LS
	Exposed population	4187	LS
	Acutely infected population	151360	LS
	Chronically infected population		LS
	Treated population	50000	LS
	Recovered population with partial immunity		LS
Parameters
	Recruitment rate	year^−1	See text
	Natural death rate	0.007 year^−1	[18, 24]
	Transmission rate of acutely infected population		LS
	Transmission rate of chronically infected population		LS
	Transmission rate of treated population		LS
	Rate of progression to acute stage from the exposed	6 year^−1	[18]
	Recovery rate for the acute state	0.5 year^−1	[15]
	Rate of moving from acute stage to chronic stage	4 year^−1	[18]
	Treatment rate of acutely infected population	0.1545 year^−1	see text
	Treatment rate of chronically infected population	0.04 year^−1	[15]
	Treatment cure rate	0.67 year^−1	[15]
	Treatment failure rate	0.82 year^−1	[15]
	HCV induced death rate at the chronic stage	0.001 year^−1	[18]
	Rate of waning immunity	0.025 year^−1	[15]

LS, least square.