Topological Descriptors and QSPR Modelling of HIV/AIDS Disease Treatment Drugs

Table 1

Physical properties of drugs.

Name of drug	Boiling point (°C)	Enthalpy (°C)	Flash point (°C)	Molar refractivity (cm^3)	Polarity (cm^3)	Molar volume (cm^3)	Complexity	Density (g/cm^3)	Polar surface area (A^2)
Vidaza	534.4	93.2	277	51.1	20.3	117.1	384	2.1	141
Lamivudine	475.4	85.2	241.3	54.1	21.5	132.2	331	1.7	113
Darunavir					56.9	408.4	853	1.3	149
Disovey	443.3	80.9	221.9	1.731	21.4	135.2	374	1.8	113
Maraviroc				141.1	55.9	397.8	751	1.3	63
Tenofovir	642.7	94.9	342.5	118.3	46.9	356.1		1.5	195
Tipranavir	712.3	109.3	384.6	152.4	60.4	459		1.3	114
Atazanavir				194	76.9	597.9	1110	1.2	171
Lopinavir	924.2	140.8	512.7	179.2	71	540.5	940	1.2	120
Abacavir	636	98.8	338.4	75.8	30.1	167.7	414	1.7	102
Etravirine	637.4	94.2	339.3	106.9	42.4	275.7	609	1.6	121
Nelfinavir	786.8	120.1	429.7	162.4	64.4	463.1	830	1.2	127
Toreforant	611.2	90.8	323	120.1	47.6	341.7	508	1.1	70