Topological Descriptors and QSPR Modelling of HIV/AIDS Disease Treatment Drugs

Table 15

Comparison of polarity.

Name of drug	Polarity of drug	Polarity computed from regression model
		ABC	R	S	GA	M1	M2	F	H	HM
Vidaza	20.3 ± 5.0 cm^3	23.09952	23.42708	22.9845	22.76874	23.182	23.709	24.393	23.16765	23.96
Lamivudine	21.5 ± 5.0 cm^3	19.94815	20.5904	20.25048	19.93051	19.402	19.034	19.873	20.67915	19.37
Darunavir	56.9	49.18702	49.36244	48.94122	48.45667	49.327	49.834	50.722	48.8703	50.18
Disovey		21.57601	21.97497	21.60102	21.32164	21.292	21.234	22.133	21.88785	21.6
Maraviroc	55.9 ± 5.0 cm^3	57.45154	56.11644	57.43974	58.53037	59.092	60.834	58.745	56.58465	59.55
Tenofovir	46.9 ± 5.0 cm^3	51.08619	51.89519	51.24702	49.99171	49.012	46.809	48.123	51.501	47.39
Tipranavir	60.4 ± 5.0 cm^3	63.98385	63.24191	64.06068	63.80707	66.022	67.709	69.141	63.0192	68.35
Atazanavir	76.9 ± 5.0 cm^3	76.79803	77.35777	76.38024	75.92749	75.472	73.759	74.339	76.8837	73.93
Lopinavir	71.00 ± 0.0 cm^3	67.97002	69.59067	69.56166	69.77134	66.022	64.959	61.005	70.698	62.65
Abacavir	30.10 ± 0.0 cm^3	31.36404	30.85648	31.77948	32.75449	32.632	34.159	32.529	31.593	33.13
Etravirine	42.4 ± 0.0 cm^3	38.39723	37.91441	37.93926	38.12713	38.302	38.284	38.179	37.74315	38.09
Nelfinavir	64.4 ± 0.0 cm^3	62.94035	61.4521	61.62312	62.19208	64.132	64.959	66.203	61.0284	65.5
Toreforant	47.6 ± 0.0 cm^3	52.10882	52.50305	52.16934	52.00645	50.902	49.834	49.705	52.5675	49.63