Topological Descriptors and QSPR Modelling of HIV/AIDS Disease Treatment Drugs

Table 17

Comparison of Enthalpy.

Name of drug	Enthalpy of drug	Enthalpy computed from regression model
		ABC	R	S	GA	M1	M2	F	H	HM
Vidaza	93.2 ± 3.0°C	86.4486	86.46836	86.1325	85.74933	86.6	86.926	88.357	86.04973	87.869
Lamivudine	85.2 ± 3.0°C	84.13075	84.3608	84.1023	83.61045	83.828	83.475	85.197	84.18003	84.539
Darunavir		105.6361	105.7375	105.407	105.1077	105.773	106.211	106.764	105.3611	106.9
Disovey		85.32805	85.38949	85.1052	84.6588	85.214	85.099	86.777	85.08817	86.159
Maraviroc		111.7147	110.7555	111.718	112.6992	112.934	114.331	112.373	111.1571	113.7
Tenofovir	94.9 ± 3.0°C	107.033	107.6192	107.119	106.2645	105.542	103.978	104.947	107.3376	104.88
Tipranavir	109.3 ± 3.0°C	116.5193	116.0495	116.634	116.6757	118.016	119.406	119.641	115.9916	120.09
Atazanavir		125.9442	126.5371	125.782	125.8096	124.946	123.872	123.275	126.4085	124.14
Lopinavir	140.8 ± 3.0°C	119.4511	120.7664	120.719	121.1703	118.016	117.376	113.953	121.761	115.95
Abacavir	98.8 ± 3.0°C	92.5272	91.98816	92.6633	93.27455	93.53	94.64	94.045	92.38	94.529
Etravirine	94.2 ± 3.0°C	97.70015	97.23197	97.2373	97.32335	97.688	97.685	97.995	97.00083	98.129
Nelfinavir	120.1 ± 3.0°C	115.7518	114.7197	114.824	115.4586	116.63	117.376	117.587	114.4959	118.02
Toreforant	90.8 ± 3.0°C	107.7851	108.0709	107.804	107.7828	106.928	106.211	106.053	108.1389	106.5