Topological Descriptors and QSPR Modelling of HIV/AIDS Disease Treatment Drugs

Table 18

Comparison of Molar refractivity.

Name of drug	Molar refractivity of drug	Molar refractivity computed from regression model
		ABC	R	S	GA	M1	M2	F	H	HM
Vidaza	51.1 ± 5.0 cm^3	129.4744	131.5672	128.2195	127.0814	131.417	136.69	142.11	129.493	139.18
Lamivudine		102.61	107.308	104.8882	102.9254	99.281	97.148	103.71	108.2263	100.182
Darunavir		351.8619	353.3656	349.7263	345.71	353.691	357.66	365.79	349.1477	362.101
Disovey		116.4869	119.1488	116.4133	114.7652	115.349	115.756	122.91	118.5559	119.154
Maraviroc		422.3142	411.1256	422.2501	431.4467	436.709	450.7	433.95	415.0744	441.678
Tenofovir	342.5 ± 3.0 cm^3	368.0517	375.0256	369.4033	358.7746	351.013	332.074	343.71	371.6296	338.386
Tipranavir	384.6 ± 3.0 cm^3	478.0001	472.0624	478.7512	476.3564	495.625	508.85	522.27	470.064	516.512
Atazanavir		587.2368	592.7808	583.8826	579.5126	575.965	560.022	566.43	588.5499	563.942
Lopinavir	512.7 ± 3.0 cm^3	511.9809	526.3568	525.6949	527.1179	495.625	485.59	453.15	535.687	468.028
Abacavir	338.4 ± 3.0 cm^3	199.9267	195.1032	203.2732	212.0696	211.757	225.078	211.23	201.496	217.176
Etravirine	339.3 ± 3.0 cm^3	259.8824	255.4624	255.8389	257.7958	259.961	259.968	259.23	254.0551	259.336
Nelfinavir	429.7 ± 3.0 cm^3	469.1046	456.756	457.9498	462.6113	479.557	485.59	497.31	453.0507	492.27
Toreforant	323 ± 3.0 cm^3	376.7693	380.224	377.2741	375.922	367.081	357.66	357.15	380.7439	357.358