Topological Descriptors and QSPR Modelling of HIV/AIDS Disease Treatment Drugs

Table 19

Comparison of Complexity.

Name of drug	Complexity of drug	Complexity computed from regression model
		ABC	R	S	GA	M1	M2	F	H	HM
Vidaza	384	358.4694	362.801	357.4323	355.1474	356.575	358.148	364.466	360.4039	360.904
Lamivudine	331	318.545	326.8708	322.8138	319.4574	308.071	297.407	304.306	329.0551	300.372
Darunavir	853	688.9694	691.3053	686.0992	678.1663	692.061	697.583	714.898	684.1922	706.918
Disovey		339.1682	344.4081	339.9145	336.9505	332.323	325.991	334.386	344.2817	329.82
Maraviroc	751	793.6718	776.8533	793.7084	804.8404	817.363	840.503	821.682	781.3735	830.436
Tenofovir		713.0298	723.3858	715.2955	697.469	688.019	658.28	680.306	717.3324	670.108
Tipranavir		876.429	867.1064	877.5435	871.1935	906.287	929.828	960.05	862.4326	946.592
Atazanavir	1110	1038.771	1045.902	1033.535	1023.605	1027.547	1008.434	1029.234	1037.09	1020.212
Lopinavir	940	926.9294	947.5215	947.1975	946.1926	906.287	894.098	851.762	959.166	871.336
Abacavir	414	463.1718	456.9038	468.7953	480.7156	477.835	493.922	472.754	466.542	481.968
Etravirine	609	552.2746	546.3014	546.7911	548.2751	550.591	547.517	547.954	544.0183	547.408
Nelfinavir	830	863.209	844.4362	846.6788	850.8854	882.035	894.098	920.946	837.3535	908.964
Toreforant	508	725.9854	731.0851	726.974	722.8039	712.271	697.583	701.362	730.7676	699.556