Topological Descriptors and QSPR Modelling of HIV/AIDS Disease Treatment Drugs

Table 20

Comparison of Boiling point.

Name of drug	Boiling point of drug	Boiling point computed from regression model
		ABC	R	S	GA	M1	M2	F	H	HM
Vidaza	534.4 ± 6.0°C	518.8633	519.6661	516.926	514.0875	520.968	524.647	535.047	516.625	529.8
Lamivudine	475.4 ± 5.0°C	498.8286	501.5204	499.4595	495.7517	497.052	495.118	507.727	500.595	501.5
Darunavir		684.7133	685.5694	682.7527	680.0389	686.387	689.662	694.186	682.192	691.9
Disovey		509.1776	510.3772	508.0875	504.7388	509.01	509.014	521.387	508.381	515.3
Maraviroc		737.2546	728.7734	737.0462	745.1179	748.17	759.142	742.679	731.885	749.7
Tenofovir	642.7.5 ± 55°C	696.7872	701.7709	697.4835	689.9557	684.394	670.555	678.477	699.138	674.6
Tipranavir	712.3 ± 37°C	778.7834	774.3537	779.3447	779.2069	792.016	802.567	805.515	773.334	804.1
Atazanavir		860.2489	864.65	858.0492	857.5083	851.806	840.781	836.933	862.644	838.5
Lopinavir	924.2 ± 55°C	804.1253	814.9654	814.4882	817.7378	792.016	785.197	756.339	822.798	768.8
Abacavir	636 ± 55°C	571.4046	567.1905	573.1135	578.5983	580.758	590.653	584.223	570.898	586.5
Etravirine	637.4 ± 55°C	616.1177	612.3387	612.4658	613.3071	616.632	616.708	618.373	610.515	617.2
Nelfinavir	786.8 ± 37°C	772.1494	762.9046	763.7721	768.7736	780.058	785.197	787.757	760.51	786.5
Toreforant	611.2 ± 55°C	703.2885	705.6593	703.3758	702.9715	696.352	689.662	688.039	706.008	688.4