Topological Descriptors and QSPR Modelling of HIV/AIDS Disease Treatment Drugs

Table 21

Comparison of flash point.

Name of drug	Flash point of drug	Flash point computed from regression model
		ABC	R	S	GA	M1	M2	F	H	HM
Vidaza	277 ± 32°C	267.5661	268.0535	266.3963	264.6722	268.815	271.007	277.327	266.2176	274.362
Lamivudine	241.3 ± 30°C	255.4514	257.0814	255.8345	253.5855	254.355	253.157	260.807	256.5247	257.194
Darunavir		367.8536	368.3696	366.6693	365.0142	368.83	370.757	373.556	366.3314	372.498
Disovey		261.7093	262.4368	261.0518	259.0196	261.585	261.557	269.067	261.2327	265.546
Maraviroc		399.6247	394.4936	399.4998	404.364	406.185	412.757	402.879	396.3794	407.53
Tenofovir	342.5 ± 31.5°C	375.1545	378.1661	375.5768	371.0103	367.625	359.207	364.057	376.5782	362.058
Tipranavir	384.6 ± 26.5°C	424.7367	422.0545	425.077	424.9758	432.695	439.007	440.875	421.4425	440.474
Atazanavir		473.9979	476.6536	472.6685	472.3205	468.845	462.107	459.873	475.4458	461.354
Lopinavir	512.7 ± 34.3°C	440.0606	446.611	446.3278	448.2734	432.695	428.507	411.139	451.352	419.13
Abacavir	338.4 ± 31.5°C	299.3372	296.7899	300.372	303.6785	304.965	310.907	307.063	299.035	308.698
Etravirine	339.3 ± 26.5°C	326.3747	324.0895	324.1678	324.665	326.655	326.657	327.713	322.9903	327.258
Nelfinavir	429.7 ± 31.5°C	420.7252	415.1316	415.6605	418.6673	425.465	428.507	430.137	413.6882	429.802
Toreforant	90.8 ± 34.3°C	379.0858	380.5173	379.1398	378.8803	374.855	370.757	369.839	380.7323	370.41