Pituitary Tumor-Transforming Gene 1 Is Expressed in Primary Ductal Breast Carcinoma, Lymph Node Infiltration, and Distant Metastases

Table 1

Baseline characteristics of matched primary breast tumors and distant metastasis.

Patient	Age at diagnosis; (years)	Histopathological features of primary tumour							Lymph; nodes^+ ratio(%)	Age at; diagnosis; (years)	Histopathological features of distant metastasis
		Histological; type	Histological; grade	Pathological; stage	ER; (%)	PR; (%)	HER-2/neu	MIB-1^+ (%)			Site	ER; (%)	PR; (%)	HER-2/neu	MIB-1^+ (%)
1	75	IDC	G2	pT2(m)N3a	15	neg	pos	40	17/24 (70.8)	76	Skin	90	neg	pos	60
2	59	IDC	G2	pT1cN3a	40	70	neg	20	19/19 (100)	64	Soft tissue	20	20	neg	3
3	73	IDC	G2	pT2N1a	40	neg	neg	10	1/12 (8.3)	77	Soft tissue	25	10	neg	20
4	35	IDC	G2	pT1cN1a	10	10	neg	15	2/10 (20)	37	Chest	5	5	neg	20
5	56	IDC	G3	pT4bN1a	100	15	neg	40	2/10 (20)	58	Bone	20	5	neg	40
6	59	IDC	G3	pT3N3a	neg	neg	neg	50	12/32 (37.5)	61	Liver	10	neg	neg	30
7	75	IDC	G3	pT2N3a	neg	neg	pos	50	12/19 (63.1)	76	Skin	neg	neg	pos	50
8	44	IDC	NA	pT1micN1a	80	70	neg	40	2/15 (13.3)	46	Liver	90	neg	pos	50

Notes. IDC: invasive ductal carcinoma; ER: estrogen receptor; PR: progesterone receptor; NA: not available; ⁺:positive.