Research Article
Association of Polymorphisms of Genes Involved in Lipid Metabolism with Blood Pressure and Lipid Values in Mexican Hypertensive Individuals
Table 1
Frequencies of genotypic and allelic polymorphisms in hypertensive and normotensive subjects.
| | APOA5 p.S19W | APOB p.E4181K | FABP2 p.A55T | LDLR c.1959C>T | LIPC −514C>T | LPL p.S474X | MTTP −493 G>T |
| HT | | % | | % | | % | | % | | % | | % | | % |
| Genotype | SS | 97 | 60.6 | EE | 88 | 55.0 | AA | 57 | 36.1 | CC | 36 | 22.5 | CC | 38 | 24.7 | SS | 142 | 88.8 | GG | 106 | 67.1 | SW | 56 | 35.0 | EK | 67 | 41.9 | AT | 47 | 29.7 | CT | 73 | 45.6 | CT | 67 | 43.5 | SX | 17 | 10.6 | GT | 48 | 30.4 | WW | 7 | 4.4 | KK | 5 | 3.1 | TT | 54 | 34.2 | TT | 51 | 31.9 | TT | 49 | 31.8 | XX | 1 | 0.6 | TT | 4 | 2.5 |
| | | % | | % | | % | | % | | % | | % | | % |
| Allele | S | 250 | 77.1 | E | 243 | 75.9 | A | 161 | 50.9 | C | 145 | 45.3 | C | 143 | 46.4 | S | 301 | 94.1 | G | 260 | 82.3 | W | 70 | 22.9 | K | 77 | 24.1 | T | 155 | 49.1 | T | 175 | 54.7 | T | 165 | 53.6 | X | 19 | 5.9 | T | 56 | 17.7 |
| NT | | % | | % | | % | | % | | % | | % | | % |
| Genotype | SS | 100 | 62.5 | EE | 111 | 69.4 | AA | 71 | 44.7 | CC | 34 | 21.2 | CC | 35 | 22.3 | SS | 135 | 84.9 | GG | 112 | 70.4 | SW | 53 | 33.1 | EK | 42 | 26.3 | AT | 35 | 22.0 | CT | 82 | 51.3 | CT | 78 | 49.7 | SX | 22 | 13.8 | GT | 42 | 26.4 | WW | 7 | 4.4 | KK | 7 | 4.3 | TT | 53 | 33.3 | TT | 44 | 27.5 | TT | 44 | 28.0 | XX | 2 | 1.3 | TT | 5 | 3.2 |
| | | % | | % | | % | | % | | % | | % | | % |
| Allele | S | 253 | 79.1 | E | 264 | 82.5 | A | 177 | 55.7 | C | 150 | 46.9 | C | 148 | 47.1 | S | 292 | 91.8 | G | 266 | 83.6 | W | 67 | 20.9 | K | 56 | 17.5 | T | 141 | 44.3 | T | 170 | 53.1 | T | 166 | 52.9 | X | 26 | 8.2 | T | 52 | 16.4 |
| genotype | 0.93 | 0.01 | 0.19 | 0.58 | 0.52 | 0.77 | 0.82 |
| allele | 0.85 | 0.04 | 0.23 | 0.69 | 0.86 | 0.27 | 0.65 |
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Due to a lack of DNA, these samples were not screened. HT: hypertensive patients. NT: normotensive subjects.
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