Clinical Significance of Survivin Expression in Patients with Urothelial Carcinoma

Table 2

Relationship between IHC expression of survivin and clinical characteristics.

	Survivin expression in tumor tissues^a			P value^b
	Low	Moderate	High
Tumor stage
Non-muscle-invasive (Ta-T1)	6 (15.8)	19 (50.0)	13 (34.2)	0.042*
Muscle-invasive (T2–T4)	3 (16.7)	3 (16.7)	12 (66.6)
Tumor grade
G1	4 (30.8)	5 (38.4)	4 (30.8)	0.0014**
G2	3 (10.4)	17 (58.6)	9 (31.0)
G3	2 (14.3)	0 (0.0)	12 (85.7)

^∗𝑃<0.05; ^∗∗𝑃<0.01. aPercentage of survivin (+) cells: low, 0–5%; moderate, 5–50%; high, >50%. bChi-square test.