Diagnostic and Prognostic Role of Preoperative Circulating CA 15-3, CA 125, and Beta-2 Microglobulin in Renal Cell Carcinoma

Table 5

Multivariate analysis for CSS (a) and PFS (b).

Variable	𝑃 value	HR	95% CI
(a) CSS
Age	0.03	0.95	0.90–0.99
T	0.76
N	0.21
M	0.0001	2.91	1.60–4.32
Fuhrman grade	0.06
CA 15-3	0.002	1.05	1.02–1.08
CA 125	0.11
β-2 microglobulin	0.97
(b) PFS
Age	0.53
T	0.001	3.09	1.95–4.91
N	0.03	3.36	1.06–10.60
M	0.0001	2.06	1.01–3.19
Fuhrman grade	0.71
CA 15-3	0.003	1.04	1.01–1.07
CA 125	0.007	0.96	0.92–0.99
β-2 microglobulin	0.51