Research Article

Study of Leptin and Adiponectin as Disease Markers in Subjects with Obstructive Sleep Apnea

Table 1

Clinical and anthropometric characteristics of the study subjects grouped by polysomnographic diagnosis of OSA and OSA severity. Results are mean (standard deviation).

 NoMildModerateSevere

Age (years)55.8 (16.3)49.1 (17.0)53.0 (16.3)50.0 (14.8)
Height (m)1.62 (0.14)1.62 (0.10)1.59 (0.12)1.63 (0.18)
BMI (Kg/m2)40.5 (11.9)43.3 (10.5)49.8 (13.9)44.4 (16.8)
Neck size (cm)42.8 (5.2)42.2 (7.5)44.6 (4.7)44.4 (3.5)
MMP2.33 (1.19)2.59 (1.37)2.70 (1.17)2.95 (1.10)*
Saturation of O2 on air (%)94.82 (2.62)94.36 (4.32)93.33 (3.45)95.42 (2.34)
Epwoth's scale7.69 (5.48)9.60 (5.39)10.89 (7.80)12.44 (7.28)*
Sleep efficiency (%)83.45 (7.84)81.44 (7.79)82.25 (10.77)81.08 (6.92)
Desaturation index 10.00 (7.45)20.06 (19.12)30.38 (20.44)49.11 (23.20)*
Total number of arousal/hr95.43 (67.09)72.73 (46.87)77.24 (62.37)69.53 (55.18)
Arousal index/hour18.39 (12.48)14.39 (9.16)16.04 (12.65)15.61 (13.89)
Basal O2 during sleep (%)92.57 (3.05)91.90 (3.71)90.18 (4.89)90.91 (4.7)
Average low O2 during all desaturation (%)88.036 (3.75)87.31 (4.24)83.75 (6.18)83.92 (5.94)
Minimum O2 value (%)65.49 (21.65)67.68 (12.87)57.90 (15.32)59.65 (13.67)
Basal heart rate (bpm)72.30 (8.62)73.57 (10.72)79.37 (9.59)75.32 (11.06)
Slowest heart rate (bpm)44.48 (8.40)40.23 (8.39)45.21 (9.02)44.41 (11.61)
Fastest heart rate (bpm)100.69 (12.46)101.51 (11.50)102.08 (11.12)104.61
Respiratory disturbance index2.6 (1.6)10.3 (3.8)18.0 (6.9)48.9 (13.1)*
Hb (g/L)136.26 (19.17)130.38 (18.95)130.88 (25.30)145.47 (18.53)
WBC ( /L) 8.16 (3.39)8.75 (2.57)9.73 (1.71)8.80 (4.01)

for trend <0.05.
MMP: modified Mallampati score, BMI: body mass index, bpm: beats per minute, Hb: hemoglobin, O2: oxygen, and WBC: white blood cells.