Association of FTO Mutations with Risk and Survival of Breast Cancer in a Chinese Population

Table 3

FTO rs1477196 and rs16953002 and breast cancer risk stratified by BMI levels.

SNP	Genotypes	BMI < 24		BMI ≥ 24
		OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)
rs1477196	GG	1.00		1.00
	GA	0.75 (0.54–1.05)	0.73 (0.52–1.02)	0.81 (0.56–1.18)	0.86 (0.58–1.27)
	AA	0.41 (0.22–0.76)	0.45 (0.24–0.85)	0.91 (0.42–1.98)	0.72 (0.34–1.52)
					0.02
rs16953002	GG	1.00		1.00
	GA	1.20 (0.85–1.69)	1.15 (0.81–1.63)	1.10 (0.74–1.63)	1.09 (0.73–1.63)
	AA	1.78 (1.07–2.96)	1.66 (0.99–2.79)	1.82 (1.01–3.27)	1.90 (1.05–3.46)
					0.15

Adjusted for age.
Adjusted for age, age at menarche, BMI, ever breastfeeding, and education.