Assessment of Cell-Cycle Arrest Biomarkers to Predict Early and Delayed Acute Kidney Injury

Table 3

Values for prediction of AKI within 12 to 48 hours.

Urine biomarker	ROC area (95% CI)
Predict AKI within 12 to 48 h ( = 94)
TIMP-2 × IGFBP7	0.40 (0.24–0.57)
NGAL	0.51 (0.36–0.67)
Cystatin C	0.43 (0.27–0.59)
Predict AKI within 12 h ( = 83)
TIMP-2 × IGFBP7	0.41 (0.12–0.71)
NGAL	0.55 (0.27–0.83)
Cystatin C	0.44 (0.12–0.75)
Predict AKI within 12 to 24 h ( = 79)
TIMP-2 × IGFBP7	0.34 (0.00–0.70)
NGAL	0.51 (0.25–0.77)
Cystatin C	0.47 (0.26–0.68)
Predict AKI within 24 to 48 h ( = 82)
TIMP-2 × IGFBP7	0.43 (0.21–0.66)
NGAL	0.47 (0.22–0.72)
Cystatin C	0.41 (0.19–0.63)