Prognostic Value of Pentraxin-3 Level in Patients with STEMI and Its Relationship with Heart Failure and Markers of Oxidative Stress

Table 7

Predictive power and optimal cut-offs of biomarkers for the prediction of combined endpoint (mortality or EF ≤40% at one year).

Predictors	AUC (95% CI)	P value	Cut-off^*	Sensitivity	Specificity
PTX3	0.756 (0.675; 0.837)	<0.001	>2.1	0.864	0.572
Troponin I (max)	0.705 (0.610; 0.801)	<0.001	>90	0.568	0.826
BNP	0.800 (0.731; 0.870)	<0.001	>500	0.636	0.827

Results are based on ROC analysis.
^*Values in ng/mL (PTX3) and pg/mL (troponin I, BNP).
AUC: area under curve; CI: confidence interval; PTX3: pentraxin-3 at 24 h after onset of myocardial infarction; BNP: B-type natriuretic peptide at 24 h after onset of myocardial infarction.