HULC and H19 Played Different Roles in Overall and Disease-Free Survival from Hepatocellular Carcinoma after Curative Hepatectomy: A Preliminary Analysis from Gene Expression Omnibus

Table 5

Univariate and multivariate regression analysis of relationship between lncRNAs and HCC clinicopathological features.

LncRNAs	Univariate analysis, OR (95% CI)	P value	Multivariate analysis, OR (95% CI)	P value
HBV infection
H19, per increase of 1 unit	1.143 (1.013–1.29)	0.03	1.14 (1.008–1.29)	0.037
MEG3, per increase of 1 unit	1.503 (0.949–2.383)	0.083
MALAT1, per increase of 1 unit	28.164 (2.179–364.071)	0.011	26.951 (2.022–359.284)	0.013
Vascular invasion
MEG3, per increase of 1 unit	1.425 (1.034–1.963)	0.031
HULC, per increase of 1 unit	0.64 (0.522–0.786)	<0.001	0.648 (0.523–0.803)	<0.001
UCA1, per increase of 1 unit	2.952 (0.822–10.601)	0.097
AFP over 200 ng/mL
H19, per increase of 1 unit	1.526 (1.352–1.723)	<0.001	1.45 (1.277–1.646)	<0.001
MEG3, per increase of 1 unit	2.304 (1.584–3.351)	<0.001	1.613 (1.1–2.365)	0.014
HULC, per increase of 1 unit	0.855 (0.726–1.007)	0.06
HOXA13, per increase of 1 unit	0.547 (0.288–1.039)	0.065
KCNQ1OT1, per increase of 1 unit	2.557 (0.992–6.592)	0.052

HBV: hepatitis B virus; AFP: α-fetoprotein; OR: odd ratios; CI: confidence intervals.