Research Article

Hemoglobin A1c Level Is Not Related to the Severity of Atherosclerosis in Patients with Acute Coronary Syndrome

Table 1

Baseline clinical characteristics according to HbA1c level.

VariablesHbA1c
1 (<6.0%)2 (6.0~6.4%)3 (≥6.5%)

Age (years)57.19 ± 12.3362.66 ± 10.1762.08 ± 12.21<0.001
Male, (%)106 (0.77)54 (0.81)59 (0.67)0.110
Hypertension, (%)63 (0.46)33 (0.49)31 (0.35)0.160
DM, (%)6 (0.04)7 (0.10)61 (0.71)<0.001
Smoking, (%) 77 (0.56)43 (0.64)41 (0.47)0.090
Previous MI, (%)15 (0.11)7 (0.10)6 (0.07)0.570
Previous PCI, (%)11 (0.08)7 (0.10)7 (0.08)0.821
SBP (mmHg)128.23 ± 22.98125.39 ± 25.89129.45 ± 21.760.551
DBP (mmHg)79.32 ± 14.5478.91 ± 16.1879.23 ± 11.630.981
HR (bpm)74.74 ± 13.3773.94 ± 14.5274.03 ± 15.350.905
LVEF (%)60.67 ± 11.0058.29 ± 13.6557.09 ± 12.410.095
TC (mmol/L)3.83 ± 0.983.96 ± 0.993.80 ± 0.900.566
TG (mmol/L)1.66 ± 1.081.54 ± 0.831.81 ± 1.150.283
HDL-C (mmol/L)0.92 ± 0.210.95 ± 0.240.87 ± 0.210.080
LDL-C (mmol/L)2.29 ± 0.872.37 ± 0.932.26 ± 0.750.709
ApoA1 (g/L)1.07 ± 0.171.09 ± 0.191.06 ± 0.190.558
ApoB (g/L)0.76 ± 0.230.79 ± 0.220.78 ± 0.200.634
Lp(a) (mg/L)189.87 ± 141.33268.17 ± 256.97200.46 ± 162.24<0.05
FBS (mmol/L)6.03 ± 1.976.33 ± 1.789.81 ± 4.78<0.001
NT-proBNP (pg/mL)863.13 ± 2648.721546.72 ± 3747.961621.95 ± 3029.240.153
hsCRP (mg/L)3.56 ± 3.584.24 ± 3.935.30 ± 4.27<0.01
ACEI/ARB, (%)117 (0.86)62 (0.94)74 (0.85)0.196
β-blocker, (%)122 (0.90)56 (0.85)77 (0.89)0.60
Statins, (%)136 (1.00)64 (0.97)84 (0.97)0.102
Gensini score49.66 ± 41.1054.28 ± 38.8262.19 ± 42.960.085

HbA1c, glycosylatedhemoglobinA1c; DM, diabetes mellitus; MI, myocardial infarction; PCI, percutaneous coronary intervention; SBP, systolic blood pressure; DBP, diastolic blood pressure; HR, heart rate; LVEF, left ventricular ejection fraction; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoA1, apolipoprotein A1; ApoB, apolipoprotein B; Lp(a), lipoprotein (a); FBS, fasting blood sugar; hsCRP, high-sensitivity C-reactive protein; ACEI, angiotensin converting enzyme inhibition; ARB, angiotensin receptor blocker.