Hypermethylation-Associated Silencing of miR-125a and miR-125b: A Potential Marker in Colorectal Cancer

Table 2

Clinicopathological features of CRC patients and BSP analysis of miR-125b in tumor tissues.

Variable	Hypermethylation and low expression	Hypermethylation and high expression	Methylation and low expression	Methylation and high expression	value
Sex					0.486
Male (46)	38	2	2	4
Female (22)	18	1	0	3
Age (years)					1.000
50 (16)	12	1	1	2
50 (52)	45	1	1	5
Histological differentiation					0.486
Good or moderate	31	3	1	4
Poor or none	25	0	1	3
Lymph node metastasis					1.000
Negative	32	1	1	4
Positive	22	2	1	3
Grade					0.686
Low grade (I + II)	31	0	1	3
High grade (III + IV)	26	2	1	4