Monitoring of Serial Presurgical and Postsurgical Changes in the Serum Proteome in a Series of Patients with Calcific Aortic Stenosis

Figure 2

Panther protein class analysis (a) and hierarchical clustering analysis (b) of the 16 proteins with differential levels in presurgical and postsurgical sera of CAS patients. In (a), the stars indicate statistically significant classes (). In (b), differences in iTRAQ ratios are color-coded. Darker black spectra show more increased levels and lighter grey spectra show more decreased levels in postsurgical sera compared with those in presurgical sera.

(a)

(b)