Toll-Like Receptor 9 Inactivation Alleviated Atherosclerotic Progression and Inhibited Macrophage Polarized to M1 Phenotype in ApoE^−/− Mice

Figure 1

Inactivation of TLR9 attenuated atherosclerotic plaque burden. Representative oil red O stained photomicrographs from aortic root (a–c) and from en face preparations of the aortic tree (e–g). Histogram represented mean ± SEM from aortic root (d) and aortic tree (f) in 7 mice. versus normal control mice, versus ApoE^−/− saline mice.

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