Toll-Like Receptor 9 Inactivation Alleviated Atherosclerotic Progression and Inhibited Macrophage Polarized to M1 Phenotype in ApoE^−/− Mice

Table 1

Lipid profile of the ApoE^−/− and wild-type mice fed on the western-type diet.

	TC (mmol/L)	TG (mmol/L)	Non-HDL (mmol/L)	HDL-C (mmol/L)
Normal control	3.25 ± 0.48	1.03 ± 0.24	1.71 ± 0.37	1.47 ± 0.54
ApoE^−/− saline	20.01 ± 3.26^#	2.84 ± 0.35^#	18.83 ± 3.1^#	0.32 ± 0.23^#
ApoE^−/− IRS869	19.61 ± 3.54^#	2.93 ± 4.46^#	17.91 ± 4.34^#	0.35 ± 0.71

The results were expressed as the mean ± SE. ^#<0.01 compared with normal control littermates; TC: total cholesterol; TG: triglycerides; HDL-C: high-density lipoprotein cholesterol.