Procalcitonin, MR-Proadrenomedullin, and Cytokines Measurement in Sepsis Diagnosis: Advantages from Test Combination

Table 5

Receiver operating characteristic (ROC) curves: areas under the curves (AUCs) characteristics and cutoff values for PCT, MR-proADM, and cytokines in sepsis patients.

Markers	AUC	Sensitivity %	Specificity %	LR+	Cutoff value
PCT	0.91	75	96	19.13	0.5
MR-proADM	0.95	92	92	11.77	1.0
IL-6	0.92	89	76	3.70	16
IL-10	0.87	78	87	6.05	3
TNF-α	0.90	86	81	4.60	5
IL-8	0.78	70	73	2.63	9
MCP-1	0.80	74	76	3.12	240
VEGF	0.67	44	89	3.97	89
IFN-γ	0.70	44	89	4.06	5
IL-1α	0.63	88	57	2.07	0.08
IL-1β	0.61	79	49	1.56	0.33
EGF	0.54	97	19	1.20	0.22
IL-2	0.64	77	53	1.65	<7
IL-4	0.67	67	70	2.27	<2