Research Article
Prognostic and Predictive Values of Subcellular Localisation of RET in Renal Clear-Cell Carcinoma
Figure 3
Association of RET expression with metastasis and prognostic function of RET in targeted drug treated patients. (a) Expression of nuclear and cytoplasmic RET in no metastatic tumours and metastatic tumours; (b) expression of nuclear and cytoplasmic RET in no postoperative metastatic tumours and postoperative metastatic tumours; unpaired -test was used to study the relationships between the covariates, , and ; (c) patients with high RET nuclear expression had significantly shorter MFS; (d) patients with high RET cytoplasmic expression had shorter median MFS, but value was not significant; (e) patients with high RET cytoplasmic expression had significantly worse PFS; (f) patients with high RET cytoplasmic expression had significantly worse OS.