Survivin as a Novel Biomarker in the Pathogenesis of Acne Vulgaris and Its Correlation to Insulin-Like Growth Factor-I

<div>Expression of IGF-I (a) and survivin (b) in the skin tissue homogenates as achieved by Western blotting. <i>β</i>-Actin was used in parallel as internal control. The right panels represent corresponding quantification of each gel analysis measured by Image J software and expressed as a <i>β</i>-actin ratio, showing higher lesional expressions of IGF-1 and survivin in the acne scar group than in the active acne group and the control group, and also lesional expressions of IGF-I in the active acne group were higher than in the control group.</div>

Disease Markers

fig3

Figure 3

Figure 3: Survivin as a Novel Biomarker in the Pathogenesis of Acne Vulgaris and Its Correlation to Insulin-Like Growth Factor-I 