Association of Circulating IGFBP1 Level with the Severity of Coronary Artery Lesions in Patients with Unstable Angina

Table 3

Logistic regression analysis.

Variables	Univariate logistic regression			Multivariate stepwise logistic regression
	Estimate	OR (95% CI)	value	Estimate	OR (95% CI)	value
Gender, male	1.674	5.331 (2.344, 12.126)	<0.001	—	—	0.630
BMI, kg/m^2	0.174	1.190 (1.025, 1.381)	0.022	—	—	0.052
Cigarette smoking	1.161	3.194 (1.411, 7.228)	0.005	1.203	3.331 (1.171, 9.477)	0.024
Hypertension	0.104	1.109 (0.521, 2.364)	0.788	—	—	—
SBP, mmHg	−0.002	0.988 (0.977, 1.019)	0.998	—	—	—
DBP, mmHg	−0.024	0.976 (0.943, 1.010)	0.168	—	—	—
Hyperlipidemia	−0.332	0.717 (0.319, 1.611)	0.421	—	—	—
TC, mmol/L	−0.368	0.692 (0.462, 1.037)	0.074	—	—	—
TG, mmol/L	0.292	1.339 (0.739, 2.426)	0.336	—	—	—
ApoB, g/L	−0.261	0.770 (0.125, 4.749)	0.779	—	—	—
HDL-C, mmol/L	−2.956	0.052 (0.010, 0.277)	0.001	−5.043	0.006 (0.001, 0.080)	<0.001
LDL-C, mmol/L	−0.367	0.693 (0.403, 1.192)	0.185	—	—	—
BNP, pg/ml	0.015	1.015 (1.004, 1.026)	0.008	—	—	0.144
IGFBP-1, ng/ml	0.088	1.091 (1.041, 1.144)	<0.001	0.157	1.170 (1.080, 1.268)	<0.001

OR: odds ratio; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; TC: total cholesterol; TG: total triglyceride; ApoB: apolipoprotein B; HDL-C: high density lipoprotein cholesterol; LDL-C: low density lipoprotein cholesterol; BNP: brain natriuretic peptide; IGFBP-1: insulin-like growth factor binding protein-1.