Association of Circulating IGFBP1 Level with the Severity of Coronary Artery Lesions in Patients with Unstable Angina

Table 4

Summary of ROC Curves.

Parameter	AUC (95% CI)	SE	value	Cutoff	Sensitivity	Specificity	Youden index
IGFBP-1	0.719 (0.626, 0.811)	0.047	<0.001	>20.861	0.448	0.933	0.381
HDL-C	0.699 (0.601, 0.796)	0.050	<0.001	<1.065	0.612	0.733	0.345
IGFBP-1 & HDL-C	0.865 (0.799, 0.931)	0.034	<0.001	>0.511	0.821	0.800	0.621

ROC: receiver operating characteristic; AUC: area under ROC curve, SE: standard error, CI: confidence interval; IGFBP-1: insulin-like growth factor binding protein-1; HDL-C: high density lipoprotein cholesterol.