A Case-Control Study of the Association between Polymorphisms in the Fibrinogen Alpha Chain Gene and Schizophrenia

Table 2

Comparison of allele frequencies and genotype distributions of three FGA tagSNPs between schizophrenic patients and healthy controls.

tagSN	Group	Genotypic association (%)					Allelic association (%)
		1/1	1/2	2/2			1	2
rs2070011	SCZ (1144)	332	586	226	1.28	0.528	1250	1038	0.36	0.550
		(29.0)	(51.2)	(19.8)			(54.6)	(45.4)
	NC (1007)	272	538	197			1082	932
		(27.0)	(53.4)	(19.6)			(53.7)	(46.3)
rs2070016	SCZ (1139)	33	318	788	4.10	0.128	384	1894	0.35	0.554
		(2.9)	(27.9)	(69.2)			(16.9)	(83.1)
	NC (966)	19	301	646			339	1593
		(2.0)	(31.1)	(66.9)			(17.5)	(82.5)
rs2070022	SCZ (1144)	845	277	22	1.23	0.541	1967	321	1.22	0.269
		(73.9)	(24.2)	(1.9)			(86.0)	(14.0)
	NC (1002)	760	226	16			1746	258
		(75.8)	(22.6)	(1.6)			(87.1)	(12.9)

alleles of rs2070011 are A and G, the alleles of rs2070016 are C and T, and the alleles of rs2070022 are C and T.
: schizophrenia; NC: normal control.