The Exploration of Peptide Biomarkers in Malignant Pleural Effusion of Lung Cancer Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry
Table 2
The 28 significant peptide peaks of malignant and tuberculosis pleural effusion in training set.
Peaks area of MPE ()
Peaks area of TPE ()
value
State
917.37
22.25 ± 8.730
10.56 ± 4.680
<0.001
4469.39
562.6 ± 326.2
184.1 ± 247.9
<0.001
1466.5
23.23 ± 16.64
8.200 ± 4.920
<0.001
2790.36
18.63 ± 11.20
9.450 ± 3.810
0.002
861.51
42.70 ± 25.67
21.08 ± 13.80
0.003
867.58
21.04 ± 19.09
6.640 ± 3.120
0.003
3443.55
97.05 ± 118.3
683.1 ± 676.5
0.004
805.31
10.11 ± 6.750
4.980 ± 2.890
0.004
871.45
40.18 ± 21.32
21.96 ± 17.91
0.011
3372.4
78.46 ± 73.91
468.1 ± 530.7
0.013
3487.48
40.72 ± 55.10
307.2 ± 365.8
0.013
4791.91
93.21 ± 128.6
13.31 ± 11.17
0.013
4778.41
25.34 ± 31.98
6.270 ± 4.790
0.016
3428.58
10.43 ± 7.260
54.79 ± 65.53
0.021
4309.66
8.720 ± 3.500
13.89 ± 7.370
0.021
3401.28
20.83 ± 16.57
102.1 ± 122.5
0.021
3356.85
9.340 ± 4.420
39.34 ± 46.30
0.022
1795.93
34.24 ± 27.78
17.47 ± 12.82
0.022
4204.24
13.23 ± 11.91
27.21 ± 19.94
0.022
3329.54
14.51 ± 6.160
44.98 ± 47.45
0.022
877.63
87.30 ± 64.51
50.13 ± 27.82
0.025
4215.49
10.39 ± 9.940
19.76 ± 13.65
0.030
4585.21
21.55 ± 10.81
14.84 ± 7.360
0.032
2234.19
48.70 ± 57.90
17.99 ± 22.07
0.035
4247.85
88.60 ± 79.24
254.6 ± 282.2
0.036
4356.04
52.36 ± 41.31
179.4 ± 226.5
0.044
4540.29
32.01 ± 20.10
20.98 ± 11.72
0.044
4327.25
5.980 ± 2.120
8.310 ± 3.930
0.044
signals showed a higher peak area in MPE. signals showed a lower peak area in MPE.
