Decreased Helios Expression in Regulatory T Cells in Acute Coronary Syndrome

Figure 6

Spearman correlation analysis of the frequency of Helios+ Tregs with circulating cytokines and HDL-C in patients in the control, SA, and ACS groups. (a) The plasma level of IL-6 was negatively correlated with the proportion of Helios+ cells in CD4+Foxp3+ T cells (, ). (b) The plasma level of TGF-beta1 was positively correlated with the proportion of Helios+ cells in CD4+Foxp3+ T cells (, ). (c) The serum level of HDL-C was positively correlated with the proportion of Helios+ cells in CD4+Foxp3+ T cells (, ). (d) The plasma level of IL-6 was negatively correlated with the CD4+Foxp3+Helios+ cell counts (, ). (e) The plasma level of TGF-beta1 was positively correlated with the CD4+Foxp3+Helios+ cell counts (, ). (f) The plasma level of HDL-C was positively correlated with the CD4+Foxp3+Helios+ cell counts (, ).

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