Clinical Study

High Sensitivity Troponins Discriminate Different Morphologies of Coronary Artery Plaques Being Assessed by Coronary Computed Tomography Angiography

Table 2

Median concentrations of biomarkers in all patients as well as in subgroups of CAD.

No plaques ()Noncalcified plaques ()Calcified plaques ()Mixed plaques () value

hsTnT, ng/ml0.005 (0.0029–0.006)0.0050 (0.0030–0.0080)0.0065 (0.0040–0.0145)0.0120 (0.0060–0.030)0.0001
hsTnI, pg/ml1.8 (1.1-2.5)1.7 (1.3-4.5)2.5 (1.3–7.0)4.5 (2.9–8.5)0.0001
NT-proBNP, pg/ml77.21 (43.88–140.5)44.30 (34.93–141.10)132.45 (45.48–1176.00)292.10 (39.78–656.90)0.053
Creatinine, μmol/l75.14 (63.7–84.0)74.23 (55.7–89.3)73.37 (66.3–81.3)80.44 (72.5–95.5)0.537
Uric acid, μmol/l279.56 (243.9–315.2)285.50 (243.9–333.1)306.32 (249.8–353.9)368.78 (279.6–458.0)0.018
Cholesterol, mmol/l5.26 (4.4-5.8)4.48 (4.1–5.9)4.82 (4.2–5.3)4.40 (3.5–5.6)0.204
LDL Cholesterol, mmol/l3.34 (2.7–4.0)2.82 (2.6–3.2)3.11 (2.5–3.6)2.36 (2.0–3.9)0.186
HDL Cholesterol, mmol/l1.37 (1.1–1.7)1.01 (0.9–1.3)1.27 (1.1–1.5)1.19 (1.0-1.5)0.105
Triglyceride, mmol/l1.53 (0.8–2.0)1.58 (1.3–1.8)1.29 (1.2–1.9)1.68 (1.3–1.9)0.740

hsTnT: high sensitivity troponin T; hsTNI: high-sensitivity troponin I; NT-proBNP: N-terminal probrain natriuretic peptide; IQR: interquartile range. Data are given as follows: medians (interquartile range).