Serum Uric Acid as an Independent Risk Factor for the Presence and Severity of Early-Onset Coronary Artery Disease: A Case-Control Study
Table 1
Demographic and clinical characteristics of EOCAD patients and controls.
Variable
EOCAD ()
Control ()
value
Gender, male (%)#
986 (90.21)
1015 (90.86)
0.597
Age, years
43.90 ± 4.61
43.83 ± 4.52
0.693
BMI (kg/m2)
26.78 ± 3.61
24.75 ± 3.38
<0.001
Hypertension, (%)#
314 (28.73)
305 (27.31)
0.578
Diabetes, (%)#
214 (19.58)
46 (4.12)
<0.001
Smoking, (%)#
533 (48.76)
446 (41.72)
<0.001
Drinking, (%)#
677 (61.94)
415 (39.92)
<0.001
FBG, mmol/l
6.06 ± 2.57
5.43 ± 1.63
<0.001
TG, mmol/l
2.15 ± 1.84
1.45 ± 1.13
<0.001
TC, mmol/l
4.54 ± 1.29
4.52 ± 1.96
0.635
HDL-C, mmol/l
1.08 ± 0.27
1.27 ± 0.33
<0.001
LDL-C, mmol/l
2.62 ± 0.99
2.51 ± 0.74
0.004
Lp(a), mmol/l
287.89 ± 331.77
205.65 ± 218.89
<0.001
SCr, μmol/l
73.33 ± 15.86
75.14 ± 13.81
0.139
UA, μmol/l
5.843 ± 1.479
5.433 ± 1.529
<0.001
Male, μmol/l
5.965 ± 1.442
5.560 ± 1.492
<0.001
Female, μmol/l
4.718 ± 1.343
4.178 ± 1.311
0.004
Myocardial infarction, (%)
633 (57.91)
—
—
1-vessel disease, (%)
326 (51.50)
—
—
2-vessel disease, (%)
199 (31.44)
—
—
3-vessel disease, (%)
108 (17.06)
—
—
EOCAD: early-onset coronary artery disease; BMI: body mass index; FBG: fasting blood glucose; TG: triglyceride; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; Lp (a): lipoprotein (a); SCr: serum creatinine; UA: uric acid. Continuous variables are expressed as mean ± SD. The value of the continuous variables was calculated by the unpaired t-test. #Categorical variables are expressed as percentages. The value of the categorical variables was calculated by test.
