Circulating Semaphorin 4D as a Marker for Predicting Radiographic Progression in Patients with Rheumatoid Arthritis

Table 4

Multivariate logistic regression analysis for radiographic progression in RA patients.

Variables	Odds ratios	95% confidence interval	values
Tacrolimus	4.757	0.912–24.808	0.064
Sema4D	1.002	1.000–1.003	0.043
Age > 60-year-old	2.352	1.029–5.374	0.043

The model included age > 60-year-old, use of hydroxychloroquine, use of tacrolimus, use of glucocorticoid, rheumatoid factor, anti-CCP, baseline total SHS, DAS28, ESR, CRP, IL-22, Sema3A, and Sema4D.