Review Article

Predictive Value of Two Polymorphisms of ERCC2, rs13181 and rs1799793, in Clinical Outcomes of Chemotherapy in Gastric Cancer Patients: A Meta-Analysis

Table 5

Association between the ERCC2 rs13181 polymorphism and overall survival of chemotherapy in gastric cancer patients.

StudyYearCountryOutcomesERCC2 rs13181ERCC2 rs1799793
AAACCCAC + CCGGGAAAGA + AA

Zheng2016ChinaOS1.0 (ref.)1.10 (0.56–2.15)1.37 (0.46–3.80)1.0 (ref.)1.12 (0.56–2.22)1.38 (0.46–3.80)
Mo2015ChinaOS1.0 (ref.)1.14 (0.58–2.28)1.35 (0.48–3.53)1.20 (0.64–2.25)1.0 (ref.)1.12 (0.57–2.20)1.93 (0.58–6.00)1.25 (0.66–2.34)
Yu2015ChinaOS1.0 (ref.)1.57 (0.93–2.65)1.0 (ref.)1.78 (1.13–2.81)
Zhong2015ChinaOS1.00 (ref)1.15 (0.63–2.10)1.76 (0.53–5.38)1.23 (0.69–2.18)
Ding2015ChinaOS1.0 (ref.)1.05 (0.68–1.62)1.0 (ref.)1.97 (1.28–3.03)
Liu2015ChinaOS1.0 (ref.)1.12 (0.44–2.88)1.0 (ref.)2.12 (0.89–5.08)
Xue2015ChinaOS1.0 (ref.)0.66 (0.39–1.11)0.44 (0.20–0.91)1.0 (ref.)0.82 (0.49–1.38)0.75 (0.31–1.71)
Yu2015ChinaOS1.0 (ref.)1.31 (0.73–2.36)1.75 (0.57–5.40)1.0 (ref.)1.52 (0.75–2.86)3.86 (1.36–12.23)
Keam2008South KoreaOS1.0 (ref.)0.49 (0.17–1.37)1.0 (ref.)0.80 (0.28–2.26)

OS: overall survival.